'Everything falls on my shoulders': SII CEO Adar Poonawalla on vaccine pressure in India


MAY 01, 2021 LONDON: Serum Institute of India CEO Adar Poonwalla on Saturday spoke out about the pressures he was under over the production of COVID-19 vaccines to meet the ever-increasing demand in India as the country battles through a devastating second wave of the coronavirus pandemic. In his first comments since he was provided with ‘Y' category security by the Indian government earlier this week, Poonawalla told ‘The Times' in an interview about receiving aggressive calls from some of the most powerful people in India, demanding supplies of Covishield -- the Oxford/AstraZeneca COVID-19 vaccine that the Serum Institute is producing in India. That pressure is largely behind his decision to fly into London to be with his wife and children, the 40-year-old entrepreneur said. "I'm staying here (London) an extended time because I don''t want to go back to that situation. Everything falls on my shoulders but I can''t do it alone...I don't want to be in a situation where you are just trying to do your job, and just because you can't supply the needs of X, Y or Z you really don't want to guess what they are going to do," Poonawalla told the newspaper. "The level of expectation and aggression is really unprecedented. It's overwhelming. Everyone feels they should get the vaccine. They can't understand why anyone else should get it before them," he said. The businessman indicated in the interview that his move to London is also linked to business plans to expand vaccine manufacturing to countries outside India, which may include the likes of the UK. "There's going to be an announcement in the next few days," he said, when asked about Britain as one of the production bases outside India. According to the newspaper, by the time the Oxford/AstraZeneca vaccine was approved in January this year, the Serum Institute of India had increased its annual production capacity from 1.5 to 2.5 billion doses at a cost of USD 800 million, and stockpiled 50 million doses of Covishield. The company began exporting to 68 countries, including Britain, as India seemed to have been over the worse, until the situation worsened in recent weeks. "We're really gasping for all the help we can get," Poonawalla said in the ‘Times' interview. "I don't think even God could have forecast it was going to get this bad," he said. On the charge of profiteering as the cost of Covishield was recently hiked, he termed it as "totally incorrect" and added that Covishield will still be "the most affordable vaccine on the planet" even at a higher price. "We have done the best we can without cutting corners or doing anything wrong or profiteering. I'll wait for history to judge," he said. "I've always had this sense of responsibility to India and the world because of the vaccines we were making, but never have we made a vaccine so needed in terms of saving lives," he added. Copyright © Jammu Links News Source: Jammu Links News
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Covid vaccine as good in `real world` as in trial


More data from Israel's vaccination programme is suggesting the Pfizer jab prevents 94% of symptomatic infections.

This indicates the vaccine is performing just as well in a larger population as it did in the clinical trials.

It is proving highly effective at preventing illness and severe disease among all age groups, according to public health doctor Prof Hagai Levine.

"High vaccination coverage of the most susceptible groups" was key, he said.

Israel's largest health fund Clalit looked at positive tests in 600,000 vaccinated people and the same number of unvaccinated people, matched by age and health status.

It found 94% fewer infections among the vaccinated group.

This was based on test results in people's medical records, usually taken if they had symptoms or were a close contact of someone who had tested positive.

And the vaccine prevented almost all cases of serious illness.

This pattern was the same in all age groups - including the over-70s, who may have been under-represented in clinical trials.

This "sends a message to other countries such as the UK" about the usefulness of the vaccine, said Prof Levine, and the need to get "very high" coverage of the groups most likely to become very ill from the virus.

He said he could not put a number on what proportion of the population would need to be immunised before restrictions could ease.

"We still don't know what the impact is on transmission," he said.

But we can say that, at least, "the vaccine is useful for personal protection", he added.

Prof Eran Segal, who is analysing data for the Israeli Ministry of Health, suggested Israel had to vaccinate 80% of its over-60s before learning of its effect on Covid-19 cases.

Israel is the first country in the world to see the impact of its vaccination programme, but it took significant population coverage and several weeks to reach this milestone.

Greater falls were seen in the over-60s who were vaccinated first and in cities that vaccinated their populations earlier - patterns not seen in earlier lockdowns. This provides strong evidence it was the vaccine, and not just the lockdown, driving down cases.

But Prof Segal warned falls had happened more slowly than expected, possibly because of the effect of the UK variant, which has become the dominant strain in Israel.

And he cautioned that, even with the "very rapid pace" of Israel's vaccination programme, there were still tens of thousands of people who were unprotected and could become severely ill if infected.

"We still have to exit our lockdown very cautiously," he said, or risk large numbers of people being hospitalised.

Israel has been experiencing a significant wave of infection and remains under strict measures - but with everyone over the age of 16 now entitled to get vaccine, the hope is at least the education system could be reopened too.

The country has also been met with criticism over questions about who should provide vaccines to the Palestinian territories.

Israel has only just also started to transfer some doses to Palestinians in the West Bank and Gaza, so that vaccinations can begin for front-line health workers.Meanwhile it has given the full two doses to a quarter of its resident population.- BBC. Source: https://www.daily-bangladesh.com
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Mexican Defense Minister tests COVID-19 positive


Mexican Defense Minister Luis Cresencio Sandoval on Wednesday said that he had tested positive for COVID-19 and is undergoing medical treatment while working from home.

The Minister said, “I will continue my duties in quarantine from home, under medical treatment, and relying on the officials of the National Defense Ministry in keeping with the chain of command.”

Mexican President Andres Manuel Lopez Obrador and several members of his cabinet have tested positive for COVID-19 since the outbreak of the pandemic in Mexico.The country’s health ministry has reported more than 2 million official cases and over 175,000 deaths, the world’s third-highest COVID-19 death toll, after the United States and Brazil. Source: https://www.daily-bangladesh.com
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